so you are starting to get jams from all of the ships being called in.

You only have one shipping lane bringing in ships.

You need like 3 strategically placed in the bay in total. Having train stations way off the road is delaying traffic, plus you are clumping several in one spot, so they are going to create train jams from so many trains in one spot. You may need another cargo train inside generic industry that connects to the outside connection line, so it can import.export freight instead of sending it through your city. Then it is easier to place one train in generic industry and another in a large commerce district to keep commerce supplied. I usually put the trains underground only. Maybe connect the two together by a single rail line, so they deliver freight directly, so they keep more trucks off the roads. Maybe place your cargo train stations inside commerce and industry districts. Try to remove them all and replace with on/off ramps. Created by the same user who made Automatic Bulldoze, Automatic Emptying is a mod that does just what its title. Automatic Bulldoze v2 automatically destroys abandoned and burned buildings. Thankfully, Cities Skylines comes with a built-in system for adding in game mods and plenty of amazing creators have created mods which fix some of the problems in the game, make things easier, or just make C:S more fun, overall. You still have streets intersecting the highways. Cities: Skylines> Workshop > mexahuks Workshop.

Auto bulldoze cities skylines